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Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients caused by heterozygous mutations in the HCN4 gene

Dilated cardiomyopathy (DCM) is a progressive heart muscle disease that can culminate with heart failure and death. Mutations in several genes can cause DCM, including hyperpolarization-activated cyclic nucleotide-gated channel (HCN4), which has a critical function in the autonomic control of the he...

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Detalles Bibliográficos
Autores principales: Yildirim, Zehra, Kojic, Ana, Yan, Christopher D., Wu, Matthew A., Vagelos, Randall, Wu, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881502/
https://www.ncbi.nlm.nih.gov/pubmed/36332467
http://dx.doi.org/10.1016/j.scr.2022.102951