Arginine limitation causes a directed DNA sequence evolution response in colorectal cancer cells

Utilization of specific codons varies significantly across organisms. Cancer represents a model for understanding DNA sequence evolution and could reveal causal factors underlying codon evolution. We found that across human cancer, arginine codons are frequently mutated to other codons. Moreover, ar...

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Detalles Bibliográficos
Autores principales: Hsu, Dennis J., Gao, Jenny, Yamaguchi, Norihiro, Pinzaru, Alexandra, Mandayam, Nandan, Liberti, Maria, Heissel, Søren, Alwaseem, Hanan, Tavazoie, Saeed, Tavazoie, Sohail F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881871/
https://www.ncbi.nlm.nih.gov/pubmed/36711568
http://dx.doi.org/10.1101/2023.01.02.521806

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