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Macrophage activation drives ovarian failure and masculinization

In humans, premature ovarian insufficiency (POI) is caused by autoimmunity and genetic factors, such as mutation of BMP15, a key ovarian determining gene. The cellular mechanisms associated with ovarian failure caused by BMP15 mutation and immune contributions to the disorder are not understood. BMP...

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Detalles Bibliográficos
Autores principales: Bravo, Paloma, Liu, Yulong, Draper, Bruce W., Marlow, Florence L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881905/
https://www.ncbi.nlm.nih.gov/pubmed/36711702
http://dx.doi.org/10.1101/2023.01.03.522645