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TCDD dysregulation of lncRNA expression, liver zonation and intercellular communication across the liver lobule
The persistent environmental aryl hydrocarbon receptor agonist and hepatotoxin TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) induces hepatic lipid accumulation (steatosis), inflammation (steatohepatitis) and fibrosis. Thousands of liver-expressed, nuclear-localized lncRNAs with regulatory potential hav...
Autores principales: | Karri, Kritika, Waxman, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881922/ https://www.ncbi.nlm.nih.gov/pubmed/36711947 http://dx.doi.org/10.1101/2023.01.07.523119 |
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