DNA supercoiling-induced shapes alter minicircle hydrodynamic properties

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DNA in cells is organized in negatively supercoiled loops. The resulting torsional and bending strain allows DNA to adopt a surprisingly wide variety of 3-D shapes. This interplay between negative supercoiling, looping, and shape influences how DNA is stored, replicated, transcribed, repaired, and l...

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Detalles Bibliográficos
Autores principales: Waszkiewicz, Radost, Ranasinghe, Maduni, Fogg, Jonathan M., Catanese, Daniel J., Ekiel-Jeżewska, Maria L., Lisicki, Maciej, Demeler, Borries, Zechiedrich, Lynn, Szymczak, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881935/
https://www.ncbi.nlm.nih.gov/pubmed/36711572
http://dx.doi.org/10.1101/2023.01.04.522747
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