Secretion encoded single-cell sequencing (SEC-seq) uncovers gene expression signatures associated with high VEGF-A secretion in mesenchymal stromal cells

Cells secrete numerous bioactive molecules essential for the function of healthy organisms. However, there are no scalable methods to link individual cell secretions to their transcriptional state. By developing and using secretion encoded single-cell sequencing (SEC-seq), which exploits hydrogel na...

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Detalles Bibliográficos
Autores principales: Udani, Shreya, Langerman, Justin, Koo, Doyeon, Baghdasarian, Sevana, Cheng, Brian, Kang, Simran, Soemardy, Citradewi, de Rutte, Joseph, Plath, Kathrin, Carlo, Dino Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881958/
https://www.ncbi.nlm.nih.gov/pubmed/36711480
http://dx.doi.org/10.1101/2023.01.07.523110

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