Defective phagocytosis leads to neurodegeneration through systemic increased innate immune signaling

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In nervous system development, disease and injury, neurons undergo programmed cell death, leaving behind cell corpses that are removed by phagocytic glia. Altered glial phagocytosis has been implicated in several neurological diseases including Alzheimer’s disease, Parkinson’s disease, and traumatic...

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Detalles Bibliográficos
Autores principales: Elguero, Johnny E., Liu, Guangmei, Tiemeyer, Katherine, Gandevia, Heena, Duro, Lauren, McCall, Kimberly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881959/
https://www.ncbi.nlm.nih.gov/pubmed/36711924
http://dx.doi.org/10.1101/2023.01.08.523170

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