Cargando…
Chromatin Remodeling Drives Immune-Fibroblast Crosstalk in Heart Failure Pathogenesis
Chronic inflammation and tissue fibrosis are common stress responses that worsen organ function, yet the molecular mechanisms governing their crosstalk are poorly understood. In diseased organs, stress-induced changes in gene expression fuel maladaptive cell state transitions and pathological intera...
Autores principales: | Alexanian, Michael, Padmanabhan, Arun, Nishino, Tomohiro, Travers, Joshua G., Ye, Lin, Lee, Clara Youngna, Sadagopan, Nandhini, Huang, Yu, Pelonero, Angelo, Auclair, Kirsten, Zhu, Ada, Teran, Barbara Gonzalez, Flanigan, Will, Kim, Charis Kee-Seon, Lumbao-Conradson, Koya, Costa, Mauro, Jain, Rajan, Charo, Israel, Haldar, Saptarsi M., Pollard, Katherine S., Vagnozzi, Ronald J., McKinsey, Timothy A., Przytycki, Pawel F., Srivastava, Deepak |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9881961/ https://www.ncbi.nlm.nih.gov/pubmed/36711864 http://dx.doi.org/10.1101/2023.01.06.522937 |
Ejemplares similares
-
BRD4 inhibition for the treatment of pathological organ fibrosis
por: Stratton, Matthew S., et al.
Publicado: (2017) -
Fat-to-heart crosstalk in health and disease
por: Lodewijks, Fleur, et al.
Publicado: (2023) -
Putting the Heat on Cardiac Fibrosis: Hsp20 Regulates Myocyte-To-Fibroblast Crosstalk
por: Major, Jennifer L., et al.
Publicado: (2019) -
Therapeutic targets for cardiac fibrosis: from old school to next-gen
por: Travers, Joshua G., et al.
Publicado: (2022) -
Disruptions in a cluster of computationally identified enhancers near FOXC1 and GMDS may influence brain development
por: Haliburton, Genevieve D. E., et al.
Publicado: (2015)