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ConDoR: Tumor phylogeny inference with a copy-number constrained mutation loss model
Tumors consist of subpopulations of cells that harbor distinct collections of somatic mutations. These mutations range in scale from single nucleotide variants (SNVs) to large-scale copy-number aberrations (CNAs). While many approaches infer tumor phylogenies using SNVs as phylogenetic markers, CNAs...
Autores principales: | Sashittal, Palash, Zhang, Haochen, Iacobuzio-Donahue, Christine A., Raphael, Benjamin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882003/ https://www.ncbi.nlm.nih.gov/pubmed/36711528 http://dx.doi.org/10.1101/2023.01.05.522408 |
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