Anionic Phospholipids Control Mechanisms of GPCR-G Protein Recognition

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G protein-coupled receptors (GPCRs) are embedded in phospholipids that strongly influence drug-stimulated signaling. Anionic lipids are particularly important for GPCR signaling complex formation, but a mechanism for this role is not understood. Using NMR spectroscopy, we visualized the impact of an...

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Detalles Bibliográficos
Autores principales: Thakur, Naveen, Ray, Arka P., Sharp, Liam, Jin, Beining, Duong, Alexander, Pour, Niloofar Gopal, Obeng, Samuel, Wijesekara, Anuradha V., Gao, Zhan-Guo, McCurdy, Christopher R., Jacobson, Kenneth A., Lyman, Edward, Eddy, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882065/
https://www.ncbi.nlm.nih.gov/pubmed/36711594
http://dx.doi.org/10.1101/2023.01.11.523010

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