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Aclarubicin stimulates RNA polymerase II elongation at closely spaced divergent promoters

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Anthracyclines are a class of widely prescribed anti-cancer drugs that disrupt chromatin by intercalating into DNA and enhancing nucleosome turnover. To understand the molecular consequences of anthracycline-mediated chromatin disruption, we utilized CUT&Tag to profile RNA polymerase II during a...

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Detalles Bibliográficos
Autores principales:	Wooten, Matthew, Takushi, Brittany, Ahmad, Kami, Henikoff, Steven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882078/ https://www.ncbi.nlm.nih.gov/pubmed/36712130 http://dx.doi.org/10.1101/2023.01.09.523323

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