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Mechanistic insights into robust cardiac I(Ks) potassium channel activation by aromatic polyunsaturated fatty acid analogues
Voltage-gated potassium (K(V)) channels are important regulators of cellular excitability and control action potential repolarization in the heart and brain. K(V) channel mutations lead to disordered cellular excitability. Loss-of-function mutations, for example, result in membrane hyperexcitability...
Autores principales: | Bohannon, Briana M., Jowais, Jessica J., Nyberg, Leif, Liin, Sara I., Larsson, H. Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882137/ https://www.ncbi.nlm.nih.gov/pubmed/36711783 http://dx.doi.org/10.1101/2023.01.12.523777 |
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