Mechanistic insights into robust cardiac I(Ks) potassium channel activation by aromatic polyunsaturated fatty acid analogues

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Voltage-gated potassium (K(V)) channels are important regulators of cellular excitability and control action potential repolarization in the heart and brain. K(V) channel mutations lead to disordered cellular excitability. Loss-of-function mutations, for example, result in membrane hyperexcitability...

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Detalles Bibliográficos
Autores principales: Bohannon, Briana M., Jowais, Jessica J., Nyberg, Leif, Liin, Sara I., Larsson, H. Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882137/
https://www.ncbi.nlm.nih.gov/pubmed/36711783
http://dx.doi.org/10.1101/2023.01.12.523777
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