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Ribosome rescue factor PELOTA modulates translation start site choice and protein isoform levels of transcription factor C/EBPα

Translation initiation at alternative start sites can dynamically control the synthesis of two or more functionally distinct protein isoforms from a single mRNA. Alternate isoforms of the hematopoietic transcription factor CCAAT-enhancer binding protein α (C/EBPα) produced from different start sites...

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Detalles Bibliográficos
Autores principales: Fernandez, Samantha G., Ferguson, Lucas, Ingolia, Nicholas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882168/
https://www.ncbi.nlm.nih.gov/pubmed/36711859
http://dx.doi.org/10.1101/2023.01.16.524343

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