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Ribosome rescue factor PELOTA modulates translation start site choice and protein isoform levels of transcription factor C/EBPα
Translation initiation at alternative start sites can dynamically control the synthesis of two or more functionally distinct protein isoforms from a single mRNA. Alternate isoforms of the hematopoietic transcription factor CCAAT-enhancer binding protein α (C/EBPα) produced from different start sites...
Autores principales: | Fernandez, Samantha G., Ferguson, Lucas, Ingolia, Nicholas T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882168/ https://www.ncbi.nlm.nih.gov/pubmed/36711859 http://dx.doi.org/10.1101/2023.01.16.524343 |
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