Decreasing ELK3 expression improves Bone Morphogenetic Protein Receptor 2 signaling and pulmonary vascular cell function in PAH

ELK3 is upregulated in blood and pulmonary vascular cells of PAH patients and may play a significant role in PAH potentially through modulating BMPR2 signaling.

Detalles Bibliográficos
Autores principales: Ali, Md Khadem, Zhao, Lan, de Jesus Perez, Vinicio, Nicolls, Mark R., Spiekerkoetter, Edda F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882174/
https://www.ncbi.nlm.nih.gov/pubmed/36711443
http://dx.doi.org/10.1101/2023.01.14.524023
Descripción
Sumario:ELK3 is upregulated in blood and pulmonary vascular cells of PAH patients and may play a significant role in PAH potentially through modulating BMPR2 signaling.

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