Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) Clostridioides difficile

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Clostridioides difficile (C. difficile), a leading cause of nosocomial infection, produces toxins that damage the colonic epithelium and results in colitis that varies from mild to fulminant. Variation in disease severity is poorly understood and has been attributed to host factors (age, immune comp...

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Detalles Bibliográficos
Autores principales: Dong, Qiwen, Lin, Huaiying, Allen, Marie-Maude, Garneau, Julian R., Sia, Jonathan K., Smith, Rita C., Haro, Fidel, McMillen, Tracy, Pope, Rosemary L., Metcalfe, Carolyn, Burgo, Victoria, Woodson, Che, Dylla, Nicholas, Kohout, Claire, Sundararajan, Anitha, Snitkin, Evan S, Young, Vincent B., Fortier, Louis-Charles, Kamboj, Mini, Pamer, Eric G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882218/
https://www.ncbi.nlm.nih.gov/pubmed/36711955
http://dx.doi.org/10.1101/2023.01.12.523823
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