Analysis of donor pancreata defines the transcriptomic signature and microenvironment of early pre-neoplastic pancreatic lesions

The adult healthy human pancreas has been poorly studied given lack of indication to obtain tissue from the pancreas in the absence of disease and rapid postmortem degradation. We obtained pancreata from brain dead donors thus avoiding any warm ischemia time. The 30 donors were diverse in age and ra...

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Detalles Bibliográficos
Autores principales: Carpenter, Eileen S., Elhossiny, Ahmed M., Kadiyala, Padma, Li, Jay, McGue, Jake, Griffith, Brian, Zhang, Yaqing, Edwards, Jacob, Nelson, Sarah, Lima, Fatima, Donahue, Katelyn L., Du, Wenting, Bischoff, Allison C., Alomari, Danyah, Watkoske, Hannah, Mattea, Michael, The, Stephanie, Espinoza, Carlos, Barrett, Meredith, Sonnenday, Christopher J., Olden, Nicholas, Peterson, Nicole, Gunchick, Valerie, Sahai, Vaibhav, Rao, Arvind, Bednar, Filip, Shi, Jiaqi, Frankel, Timothy L., Di Magliano, Marina Pasca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882230/
https://www.ncbi.nlm.nih.gov/pubmed/36712058
http://dx.doi.org/10.1101/2023.01.13.523300

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