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Conserved Roles for the Dynein Intermediate Chain and Ndel1 in Assembly and Activation of Dynein
Cytoplasmic dynein, the primary retrograde microtubule transport motor within cells, must be activated for processive motility through the regulated assembly of a dynein-dynactin-adapter (DDA) complex. The interaction between dynein and dynactin was initially ascribed to the N-terminus of the dynein...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882231/ https://www.ncbi.nlm.nih.gov/pubmed/36711700 http://dx.doi.org/10.1101/2023.01.13.523097 |