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Conserved Roles for the Dynein Intermediate Chain and Ndel1 in Assembly and Activation of Dynein

Cytoplasmic dynein, the primary retrograde microtubule transport motor within cells, must be activated for processive motility through the regulated assembly of a dynein-dynactin-adapter (DDA) complex. The interaction between dynein and dynactin was initially ascribed to the N-terminus of the dynein...

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Detalles Bibliográficos
Autores principales: Okada, Kyoko, Iyer, Bharat R., Lammers, Lindsay G., Gutierrez, Pedro, Li, Wenzhe, Markus, Steven M., McKenney, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882231/
https://www.ncbi.nlm.nih.gov/pubmed/36711700
http://dx.doi.org/10.1101/2023.01.13.523097