Cargando…
Biophysical modeling with variational autoencoders for bimodal, single-cell RNA sequencing data
We motivate and present biVI, which combines the variational autoencoder framework of scVI with biophysically motivated, bivariate models for nascent and mature RNA distributions. While previous approaches to integrate bimodal data via the variational autoencoder framework ignore the causal relation...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882246/ https://www.ncbi.nlm.nih.gov/pubmed/36712140 http://dx.doi.org/10.1101/2023.01.13.523995 |