Comparison of cell response to chromatin and DNA damage

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DNA-targeting drugs may damage DNA or chromatin. Many anti-cancer drugs damage both, making it difficult to understand their mechanisms of action. Using molecules causing DNA breaks without altering nucleosome structure (bleomycin) or destabilizing nucleosomes without damaging DNA (curaxin), we inve...

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Detalles Bibliográficos
Autores principales: Luzhin, Artyom, Rajan, Priyanka, Safina, Alfiya, Leonova, Katerina, Stablewski, Aimee, Wang, Jianmin, Pal, Mahadeb, Kantidze, Omar, Gurova, Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882266/
https://www.ncbi.nlm.nih.gov/pubmed/36711582
http://dx.doi.org/10.1101/2023.01.17.524424
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