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Stochastic motion and transcriptional dynamics of pairs of distal DNA loci on a compacted chromosome

Chromosomes in the eukaryotic nucleus are highly compacted. However, for many functional processes, including transcription initiation, the 3D pair-wise motion of distal chromosomal elements, such as enhancers and promoters, is essential and necessitates dynamic fluidity. Therefore, the interplay of...

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Detalles Bibliográficos
Autores principales: Brückner, David B., Chen, Hongtao, Barinov, Lev, Zoller, Benjamin, Gregor, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882297/
https://www.ncbi.nlm.nih.gov/pubmed/36711618
http://dx.doi.org/10.1101/2023.01.18.524527