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Reduced glycolysis links resting zone chondrocyte proliferation in the growth plate

A gain-of-function mutation of the chondrocyte-specific microRNA, miR-140-5p, encoded by the MIR140 gene, causes spondyloepiphyseal dysplasia, Nishimura type (SEDN, also known as SED, MIR140 type; MIM, 611894). We reported that a mouse model for SEDN showed a unique growth plate phenotype that is ch...

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Detalles Bibliográficos
Autores principales: Kobayashi, Tatsuya, Young, Cameron, Zhou, Wen, Rhee, Eugene P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882305/
https://www.ncbi.nlm.nih.gov/pubmed/36711926
http://dx.doi.org/10.1101/2023.01.18.524550