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Damage-induced pyroptosis drives endog thymic regeneration via induction of Foxn1 by purinergic receptor activation

Endogenous thymic regeneration is a crucial process that allows for the renewal of immune competence following stress, infection or cytoreductive conditioning. Fully understanding the molecular mechanisms driving regeneration will uncover therapeutic targets to enhance regeneration. We previously de...

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Detalles Bibliográficos
Autores principales:	Kinsella, Sinéad, Evandy, Cindy A., Cooper, Kirsten, Cardinale, Antonella, Iovino, Lorenzo, deRoos, Paul, Hopwo, Kayla S., Smith, Colton W., Granadier, David, Sullivan, Lucas B., Velardi, Enrico, Dudakov, Jarrod A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882324/ https://www.ncbi.nlm.nih.gov/pubmed/36711570 http://dx.doi.org/10.1101/2023.01.19.524800

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