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Novel keto-alkyl-pyridinium antifungal molecules active in models of in vivo Candida albicans vascular catheter infection and ex vivo Candida auris skin colonization
New antifungal therapies are needed for both systemic, invasive infections as well as superficial infections of mucosal and skin surfaces as well as biofilms associated with medical devices. The resistance of biofilm and biofilm-like growth phases of fungi contributes to the poor efficacy of systemi...
Autores principales: | Beattie, Sarah R., Esan, Taiwo, Zarnowski, Robert, Eix, Emily, Nett, Jeniel E., Andes, David R., Hagen, Timothy, Krysan, Damian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882332/ https://www.ncbi.nlm.nih.gov/pubmed/36711909 http://dx.doi.org/10.1101/2023.01.19.524835 |
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