Cargando…

Netrin-1 binding to Unc5B regulates Blood-Retina Barrier integrity

BACKGROUND: The blood brain barrier (BBB) preserves neuronal function in the central nervous system (CNS) by tightly controlling metabolite exchanges with the blood. In the eye, the retina is likewise protected by the blood-retina barrier (BRB) to maintain phototransduction. We showed that the secre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Furtado, Jessica, Geraldo, Luiz Henrique, Leser, Felipe Saceanu, Poulet, Mathilde, Park, Hyojin, Pibouin-Fragner, Laurence, Eichmann, Anne, Boyé, Kevin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882365/ https://www.ncbi.nlm.nih.gov/pubmed/36711611 http://dx.doi.org/10.1101/2023.01.21.525006

Ejemplares similares

Endothelial Unc5B controls blood-brain barrier integrity
por: Boyé, Kevin, et al.
Publicado: (2022)

Netrin (UNC-6) mediates dendritic self-avoidance
por: Smith, Cody J., et al.
Publicado: (2012)

Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis
por: Genet, Gael, et al.
Publicado: (2019)

UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity
por: Wang, Zheng, et al.
Publicado: (2014)

Selecting synaptic partners: GRASPing the role of UNC-6/netrin
por: Ch'ng, QueeLim
Publicado: (2011)

The UNC-6/Netrin receptors UNC-40/DCC and UNC-5 inhibit growth cone filopodial protrusion via UNC-73/Trio, Rac-like GTPases and UNC-33/CRMP
por: Norris, Adam D., et al.
Publicado: (2014)

A Systematic Analysis of the Role of Unc-5 Netrin Receptor A (UNC5A) in Human Cancers
por: Zhou, Zonglang, et al.
Publicado: (2022)

Experimental evidence for UNC-6 (netrin) axon guidance by stochastic fluctuations of intracellular UNC-40 (DCC) outgrowth activity
por: Kulkarni, Gauri, et al.
Publicado: (2013)

UNC-6 (Netrin) Orients the Invasive Membrane of the Anchor Cell in C. elegans
por: Ziel, Joshua W., et al.
Publicado: (2008)

Molecular characterization of the netrin-1 UNC-5 receptor in Lucilia sericata larvae
por: Karamzadeh, Tahereh, et al.
Publicado: (2019)

Extracellular Matrix Regulates UNC-6 (Netrin) Axon Guidance by Controlling the Direction of Intracellular UNC-40 (DCC) Outgrowth Activity
por: Yang, Yong, et al.
Publicado: (2014)

TOM-1/tomosyn acts with the UNC-6/netrin receptor UNC-5 to inhibit growth cone protrusion in Caenorhabditis elegans
por: Mahadik, Snehal S., et al.
Publicado: (2023)

The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization
por: Zhang, Feng, et al.
Publicado: (2016)

Syntaxin-1 is necessary for UNC5A-C/Netrin-1-dependent macropinocytosis and chemorepulsion
por: Martínez-Mármol, Ramón, et al.
Publicado: (2023)

A short isoform of the UNC-6/Netrin receptor UNC-5 is required for growth cone polarity and robust growth cone protrusion in Caenorhabditis elegans
por: Mahadik, Snehal S., et al.
Publicado: (2023)

A short isoform of the UNC-6/Netrin receptor UNC-5 is required for growth cone polarity and robust growth cone protrusion in Caenorhabditis elegans
por: Mahadik, Snehal S., et al.
Publicado: (2023)

PKC α regulates netrin-1/UNC5B-mediated survival pathway in bladder cancer
por: Liu, Jiao, et al.
Publicado: (2014)

Netrin-1 promotes glioma growth by activating NF-κB via UNC5A
por: Chen, Jing-Ying, et al.
Publicado: (2017)

Growth cone repulsion to Netrin-1 depends on lipid raft microdomains enriched in UNC5 receptors
por: Hernaiz-Llorens, Marc, et al.
Publicado: (2020)

Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation
por: Zarkada, Georgia, et al.
Publicado: (2021)

Expression and Relationship of Netrin-1, DCC, UNC5B, and VEGF in Villous Tissues of Patients with Delayed Abortion
por: Dong, Fen, et al.
Publicado: (2022)

Expression of netrin-1 receptors in retina of oxygen-induced retinopathy in mice
por: Liu, Dan, et al.
Publicado: (2014)

Netrin-1 inducing antiapoptotic effect of acute myeloid leukemia cells in a concentration-dependent manner through the Unc-5 netrin receptor B-focal adhesion kinase axis
por: Zhang, Kainan, et al.
Publicado: (2023)

Dorsal horn interneuron-derived Netrin-4 contributes to spinal sensitization in chronic pain via Unc5B
por: Hayano, Yasufumi, et al.
Publicado: (2016)

Downregulation of the Netrin-1 Receptor UNC5b Underlies Increased Placental Angiogenesis in Human Gestational Diabetes Mellitus
por: Prieto, Catalina P., et al.
Publicado: (2019)

The netrin receptor UNC-40/DCC assembles a postsynaptic scaffold and sets the synaptic content of GABA(A) receptors
por: Zhou, Xin, et al.
Publicado: (2020)

Retracted: Expression and Relationship of Netrin-1, DCC, UNC5B, and VEGF in Villous Tissues of Patients with Delayed Abortion
por: Imaging, Contrast Media & Molecular
Publicado: (2023)

Flavin monooxygenases regulate Caenorhabditis elegans axon guidance and growth cone protrusion with UNC-6/Netrin signaling and Rac GTPases
por: Gujar, Mahekta R., et al.
Publicado: (2017)

Actin assembly and non-muscle myosin activity drive dendrite retraction in an UNC-6/Netrin dependent self-avoidance response
por: Sundararajan, Lakshmi, et al.
Publicado: (2019)

Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer’s disease pathologies
por: Chen, Guiqin, et al.
Publicado: (2021)

An Uncommon Lung Neoplasm in a Young Patient: Diagnostic Challenges
por: Leser, Felipe Saceanu, et al.
Publicado: (2020)

Netrin-1 induces the anti-apoptotic and pro-survival effects of B-ALL cells through the Unc5b-MAPK axis
por: Huang, Lan, et al.
Publicado: (2022)

CCL21-CCR7 signaling promotes microglia/macrophage recruitment and chemotherapy resistance in glioblastoma
por: Geraldo, Luiz Henrique, et al.
Publicado: (2023)

Two alleles of unc-52 locus disrupting potential cell-binding motif of UNC-52
por: Wilsey, Rachel, et al.
Publicado: (2020)

Vascular Endothelial Growth Factor Receptor 3 Controls Neural Stem Cell Activation in Mice and Humans
por: Han, Jinah, et al.
Publicado: (2015)

Involvement of Netrin/Unc-5 Interaction in Ciliary Beating and in Pattern Formation of the Ciliary Band-Associated Strand (CBAS) in the Sea Urchin, Hemicentrotus pulcherrimus
por: Katow, Hideki, et al.
Publicado: (2020)

An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina
por: Visser, Jasper J, et al.
Publicado: (2015)

The Wnt Frizzled Receptor MOM-5 Regulates the UNC-5 Netrin Receptor through Small GTPase-Dependent Signaling to Determine the Polarity of Migrating Cells
por: Levy-Strumpf, Naomi, et al.
Publicado: (2015)

RHO-1 and the Rho GEF RHGF-1 interact with UNC-6/Netrin signaling to regulate growth cone protrusion and microtubule organization in Caenorhabditis elegans
por: Gujar, Mahekta R., et al.
Publicado: (2019)

Netrin‐1 upregulates GPX4 and prevents ferroptosis after traumatic brain injury via the UNC5B/Nrf2 signaling pathway
por: Zhang, Yuanda, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6sq7afnk05ulhkarb5um20eglc