Cytosolic and mitochondrial translation elongation are coordinated through the molecular chaperone TRAP1 for the synthesis and import of mitochondrial proteins

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A complex interplay between mRNA translation and cellular respiration has been recently unveiled, but its regulation in humans is poorly characterized in either health or disease. Cancer cells radically reshape both biosynthetic and bioenergetic pathways to sustain their aberrant growth rates. In th...

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Detalles Bibliográficos
Autores principales: Avolio, Rosario, Agliarulo, Ilenia, Criscuolo, Daniela, Sarnataro, Daniela, Auriemma, Margherita, Pennacchio, Sara, Calice, Giovanni, Ng, Martin Y., Giorgi, Carlotta, Pinton, Paolo, Cooperman, Barry, Landriscina, Matteo, Esposito, Franca, Matassa, Danilo Swann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882373/
https://www.ncbi.nlm.nih.gov/pubmed/36712063
http://dx.doi.org/10.1101/2023.01.19.524708
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