Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein

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Double homeobox (DUX) genes are unique to eutherian mammals and normally expressed transiently during zygotic genome activation. The canonical member, DUX4, is involved in facioscapulohumeral muscular dystrophy (FSHD) and cancer, when misexpressed in other contexts. We evaluate the 3 human DUX genes...

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Detalles Bibliográficos
Autores principales: Bosnakovski, Darko, Toso, Erik A., Ener, Elizabeth T., Gearhart, Micah D., Yin, Lulu, Lüttmann, Felipe F., Magli, Alessandro, Shi, Ke, Kim, Johnny, Aihara, Hideki, Kyba, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882399/
https://www.ncbi.nlm.nih.gov/pubmed/36711898
http://dx.doi.org/10.1101/2023.01.21.524976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882399/
https://www.ncbi.nlm.nih.gov/pubmed/36711898
http://dx.doi.org/10.1101/2023.01.21.524976

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