Cargando…
Impact of Childhood Trauma and Adult Separation Anxiety Disorder on Quality of Life in Individuals with Schizophrenia
BACKGROUND: Childhood trauma and anxiety disorders are common in individuals with schizophrenia. This study aimed to investigate the effects of childhood trauma and adult separation anxiety disorder on the quality of life of individuals with schizophrenia. METHODS: This cross-sectional study include...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882412/ https://www.ncbi.nlm.nih.gov/pubmed/36714165 http://dx.doi.org/10.2147/NDT.S391897 |
_version_ | 1784879288386846720 |
---|---|
author | Karaytuğ, Mahmut Onur Tamam, Lut Demirkol, Mehmet Emin Namlı, Zeynep Gürbüz, Mahmut Yeşiloğlu, Caner |
author_facet | Karaytuğ, Mahmut Onur Tamam, Lut Demirkol, Mehmet Emin Namlı, Zeynep Gürbüz, Mahmut Yeşiloğlu, Caner |
author_sort | Karaytuğ, Mahmut Onur |
collection | PubMed |
description | BACKGROUND: Childhood trauma and anxiety disorders are common in individuals with schizophrenia. This study aimed to investigate the effects of childhood trauma and adult separation anxiety disorder on the quality of life of individuals with schizophrenia. METHODS: This cross-sectional study included 111 individuals with schizophrenia and 85 control subjects. The separation anxiety symptom inventory (SASI), adult separation anxiety questionnaire (ASAQ), Positive and Negative Syndrome Scale (PANSS), childhood trauma questionnaire (CTQ), and World Health Organization quality of life questionnaire (WHOQoL-BREF) were administered to the participants. RESULTS: More individuals with schizophrenia than control subjects were unemployed and single (p<0.05). Individuals with schizophrenia scored significantly higher on the SASI, ASAQ, and CTQ (p<0.05), whereas the control subjects scored significantly higher on the WHOQoL-BREF (p<0.05). ASAQ scores had mild positive correlations with total PANSS and PANSS subscale scores, and moderate positive correlations with total CTQ, CTQ emotional subscale scores, and CTQ physical abuse subscale scores. A negative moderate correlation was found between ASAQ and total WHOQoL-BREF scores. Mediation analysis revealed that CTQ scores significantly affected total WHOQoL-BREF and ASAQ scores. The model pathway for ASAQ scores showed a significant direct and indirect effect of CTQ on the total WHOQoL-BREF scores. CONCLUSION: Childhood trauma predicts adult separation anxiety disorder, which partially mediates the impact of childhood trauma on quality of life in individuals with schizophrenia. Therapeutic interventions for adult separation anxiety disorder in individuals with schizophrenia and a history of childhood trauma may help increase their quality of life. |
format | Online Article Text |
id | pubmed-9882412 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-98824122023-01-28 Impact of Childhood Trauma and Adult Separation Anxiety Disorder on Quality of Life in Individuals with Schizophrenia Karaytuğ, Mahmut Onur Tamam, Lut Demirkol, Mehmet Emin Namlı, Zeynep Gürbüz, Mahmut Yeşiloğlu, Caner Neuropsychiatr Dis Treat Original Research BACKGROUND: Childhood trauma and anxiety disorders are common in individuals with schizophrenia. This study aimed to investigate the effects of childhood trauma and adult separation anxiety disorder on the quality of life of individuals with schizophrenia. METHODS: This cross-sectional study included 111 individuals with schizophrenia and 85 control subjects. The separation anxiety symptom inventory (SASI), adult separation anxiety questionnaire (ASAQ), Positive and Negative Syndrome Scale (PANSS), childhood trauma questionnaire (CTQ), and World Health Organization quality of life questionnaire (WHOQoL-BREF) were administered to the participants. RESULTS: More individuals with schizophrenia than control subjects were unemployed and single (p<0.05). Individuals with schizophrenia scored significantly higher on the SASI, ASAQ, and CTQ (p<0.05), whereas the control subjects scored significantly higher on the WHOQoL-BREF (p<0.05). ASAQ scores had mild positive correlations with total PANSS and PANSS subscale scores, and moderate positive correlations with total CTQ, CTQ emotional subscale scores, and CTQ physical abuse subscale scores. A negative moderate correlation was found between ASAQ and total WHOQoL-BREF scores. Mediation analysis revealed that CTQ scores significantly affected total WHOQoL-BREF and ASAQ scores. The model pathway for ASAQ scores showed a significant direct and indirect effect of CTQ on the total WHOQoL-BREF scores. CONCLUSION: Childhood trauma predicts adult separation anxiety disorder, which partially mediates the impact of childhood trauma on quality of life in individuals with schizophrenia. Therapeutic interventions for adult separation anxiety disorder in individuals with schizophrenia and a history of childhood trauma may help increase their quality of life. Dove 2023-01-23 /pmc/articles/PMC9882412/ /pubmed/36714165 http://dx.doi.org/10.2147/NDT.S391897 Text en © 2023 Karaytuğ et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Karaytuğ, Mahmut Onur Tamam, Lut Demirkol, Mehmet Emin Namlı, Zeynep Gürbüz, Mahmut Yeşiloğlu, Caner Impact of Childhood Trauma and Adult Separation Anxiety Disorder on Quality of Life in Individuals with Schizophrenia |
title | Impact of Childhood Trauma and Adult Separation Anxiety Disorder on Quality of Life in Individuals with Schizophrenia |
title_full | Impact of Childhood Trauma and Adult Separation Anxiety Disorder on Quality of Life in Individuals with Schizophrenia |
title_fullStr | Impact of Childhood Trauma and Adult Separation Anxiety Disorder on Quality of Life in Individuals with Schizophrenia |
title_full_unstemmed | Impact of Childhood Trauma and Adult Separation Anxiety Disorder on Quality of Life in Individuals with Schizophrenia |
title_short | Impact of Childhood Trauma and Adult Separation Anxiety Disorder on Quality of Life in Individuals with Schizophrenia |
title_sort | impact of childhood trauma and adult separation anxiety disorder on quality of life in individuals with schizophrenia |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882412/ https://www.ncbi.nlm.nih.gov/pubmed/36714165 http://dx.doi.org/10.2147/NDT.S391897 |
work_keys_str_mv | AT karaytugmahmutonur impactofchildhoodtraumaandadultseparationanxietydisorderonqualityoflifeinindividualswithschizophrenia AT tamamlut impactofchildhoodtraumaandadultseparationanxietydisorderonqualityoflifeinindividualswithschizophrenia AT demirkolmehmetemin impactofchildhoodtraumaandadultseparationanxietydisorderonqualityoflifeinindividualswithschizophrenia AT namlızeynep impactofchildhoodtraumaandadultseparationanxietydisorderonqualityoflifeinindividualswithschizophrenia AT gurbuzmahmut impactofchildhoodtraumaandadultseparationanxietydisorderonqualityoflifeinindividualswithschizophrenia AT yesiloglucaner impactofchildhoodtraumaandadultseparationanxietydisorderonqualityoflifeinindividualswithschizophrenia |