Genomic heterogeneity as a barrier to precision oncology in urothelial cancer

Precision oncology relies on the accurate molecular characterization of individual patients with cancer at the time of treatment initiation. However, tumor molecular profiles are not static, and cancers continually evolve because of ongoing mutagenesis and clonal selection. Here, we performed genomi...

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Detalles Bibliográficos
Autores principales: Clinton, Timothy N., Chen, Ziyu, Wise, Hannah, Lenis, Andrew T., Chavan, Shweta, Donoghue, Mark T.A., Almassi, Nima, Chu, Carissa E., Dason, Shawn, Rao, Pavitra, Rodrigues, James A., Vasani, Naresh B., Ridouani, Fourat, Rosenberg, Jonathan E., Bajorin, Dean F., Teo, Min Yuen, Bochner, Bernard H., Berger, Michael F., Ostrovnaya, Irina, Pietzak, Eugene J., Iyer, Gopa, Gao, Sizhi Paul, Hu, Wenhuo, Al-Ahmadie, Hikmat A., Solit, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882421/
https://www.ncbi.nlm.nih.gov/pubmed/36543146
http://dx.doi.org/10.1016/j.celrep.2022.111859

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