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Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases

Genome-wide association studies (GWAS) of human complex traits or diseases often implicate genetic loci that span hundreds or thousands of genetic variants, many of which have similar statistical significance. While statistical fine-mapping in individuals of European ancestries has made important di...

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Detalles Bibliográficos
Autores principales: Yuan, Kai, Longchamps, Ryan J., Pardiñas, Antonio F., Yu, Mingrui, Chen, Tzu-Ting, Lin, Shu-Chin, Chen, Yu, Lam, Max, Liu, Ruize, Xia, Yan, Guo, Zhenglin, Shi, Wenzhao, Shen, Chengguo, Daly, Mark J., Neale, Benjamin M., Feng, Yen-Chen A., Lin, Yen-Feng, Chen, Chia-Yen, O’Donovan, Michael, Ge, Tian, Huang, Hailiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882563/
https://www.ncbi.nlm.nih.gov/pubmed/36711496
http://dx.doi.org/10.1101/2023.01.07.23284293