Spatiotemporal immune atlas of the first clinical-grade, gene-edited pig-to-human kidney xenotransplant

Pig-to-human xenotransplantation is rapidly approaching the clinical arena; however, it is unclear which immunomodulatory regimens will effectively control human immune responses to pig xenografts. We transplanted a gene-edited pig kidney into a brain-dead human recipient on pharmacologic immunosupp...

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Detalles Bibliográficos
Autores principales: Cheung, Matthew D., Asiimwe, Rebecca, Erman, Elise N., Fucile, Christopher F., Liu, Shanrun, Sun, Chiao-Wang, Hanumanthu, Vidya Sagar, Pal, Harish C., Wright, Emma D., Ghajar-Rahimi, Gelare, Epstein, Daniel, Orandi, Babak J., Kumar, Vineeta, Anderson, Douglas J., Greene, Morgan E., Bell, Markayla, Yates, Stefani, Moore, Kyle H., LaFontaine, Jennifer, Killian, John T., Baker, Gavin, Perry, Jackson, Reed, Rhiannon, Little, Shawn C., Rosenberg, Alexander F., George, James F., Locke, Jayme E., Porrett, Paige M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882594/
https://www.ncbi.nlm.nih.gov/pubmed/36711785
http://dx.doi.org/10.21203/rs.3.rs-2382345/v1

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