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Focused ultrasound-mediated brain genome editing
Gene editing in the mammalian brain has been challenging because of the restricted transport imposed by the blood-brain barrier (BBB). Current approaches rely on local injection to bypass the BBB. However, such administration is highly invasive and not amenable to treating certain delicate regions o...
Autores principales: | Leong, Kam, Lao, Yeh-Hsing, Ji, Robin, Zhou, Joyce, Snow, Kathy, Kwon, Nancy, Saville, Ethan, He, Siyu, Chauhan, Shradha, Chi, Chun-Wei, Datta, Malika, Zhang, Hairong, Quek, Chai Hoon, Cai, Sarah, Li, Mingqiang, Gaitan, Yaned, Bechtel, Lawrence, Wu, Shih-Ying, Lutz, Cathleen, Tomer, Raju, Murray, Stephen, Chavez, Alejandro, Konofagou, Elisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882596/ https://www.ncbi.nlm.nih.gov/pubmed/36712096 http://dx.doi.org/10.21203/rs.3.rs-2365576/v1 |
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