Focused ultrasound-mediated brain genome editing

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Gene editing in the mammalian brain has been challenging because of the restricted transport imposed by the blood-brain barrier (BBB). Current approaches rely on local injection to bypass the BBB. However, such administration is highly invasive and not amenable to treating certain delicate regions o...

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Detalles Bibliográficos
Autores principales: Leong, Kam, Lao, Yeh-Hsing, Ji, Robin, Zhou, Joyce, Snow, Kathy, Kwon, Nancy, Saville, Ethan, He, Siyu, Chauhan, Shradha, Chi, Chun-Wei, Datta, Malika, Zhang, Hairong, Quek, Chai Hoon, Cai, Sarah, Li, Mingqiang, Gaitan, Yaned, Bechtel, Lawrence, Wu, Shih-Ying, Lutz, Cathleen, Tomer, Raju, Murray, Stephen, Chavez, Alejandro, Konofagou, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882596/
https://www.ncbi.nlm.nih.gov/pubmed/36712096
http://dx.doi.org/10.21203/rs.3.rs-2365576/v1
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