Post-fast refeeding enhances intestinal stem cell-mediated regeneration and tumourigenesis through mTORC1-dependent polyamine synthesis

For more than a century, fasting regimens have improved health, lifespan, and tissue regeneration in diverse organisms, including humans. However, how fasting and post-fast refeeding impact adult stem cells and tumour formation has yet to be explored in depth. Here, we demonstrate that post-fast ref...

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Detalles Bibliográficos
Autores principales: Imada, Shinya, Shin, Heaji, Khawaled, Saleh, Meckelmann, Sven W., Whittaker, Charles A., Corrêa, Renan Oliveira, Pradhan, Dikshant, Calibasi-Kocal, Gizem, Melo, Luiza Martins Nascentes, Allies, Gabriele, Wittenhofer, Pia, Schmitz, Oliver J., Roper, Jatin, Vinolo, Marco Aurelio Ramirez, Cheng, Chia-Wei, Tasdogan, Alpaslan, Yilmaz, Ömer H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882602/
https://www.ncbi.nlm.nih.gov/pubmed/36711807
http://dx.doi.org/10.21203/rs.3.rs-2320717/v1

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