Characterization of Chimeric Antigen Receptor Modified T Cells Expressing scFv-IL-13Rα2 after Radiolabeling with 89Zirconium Oxine for PET Imaging

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BACKGROUND: Chimeric antigen receptor (CAR) T cell therapy is an exciting cell-based cancer immunotherapy. Unfortunately, CAR-T cell therapy is associated with serious toxicities such as cytokine release syndrome (CRS) and neurotoxicity. The mechanism of these serious adverse events (SAEs) and how h...

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Detalles Bibliográficos
Autores principales: Leland, Pamela, Kumar, Dhiraj, Nimaggada, Sridhar, Bauer, Steven R, Puri, Raj K, Joshi, Bharat H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882610/
https://www.ncbi.nlm.nih.gov/pubmed/36711796
http://dx.doi.org/10.21203/rs.3.rs-2242559/v1
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