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Paneth cells as the origin of intestinal cancer in the context of inflammation

Paneth cells (PCs), responsible for the secretion of antimicrobial peptides in the small intestine and for niche support to Lgr5(+) crypt-base columnar stem cells (CBCs), have been shown to respond to inflammation by dedifferentiating into stem-like cells in order to sustain a regenerative response(...

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Detalles Bibliográficos
Autores principales:	Verhagen, Mathijs P., Joosten, Rosalie, Schmitt, Mark, Sacchetti, Andrea, Choi, Jiahn, Välimäki, Niko, Aaltonen, Lauri A., Augenlicht, Leonard H., Fodde, Riccardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882659/ https://www.ncbi.nlm.nih.gov/pubmed/36711533 http://dx.doi.org/10.21203/rs.3.rs-2458794/v1

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