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A multicomponent intranasal adjuvant drives durable humoral, cellular, and mucosal immune responses to SARS-CoV-2 in young and aged mice
Multiple FDA-approved SARS-CoV-2 vaccines provide excellent protection against severe disease. Despite this, immunity can wane relatively fast, particularly in the elderly and novel viral variants capable of evading infection- and vaccination-induced immunity continue to emerge. Intranasal (IN) vacc...
Autores principales: | Jangra, Sonia, Landers, Jeffrey J., Laghlali, Gabriel, Rathnasinghe, Raveen, O’Konek, Jessica. J., Janczak, Katarzyna W., García-Sastre, Adolfo, Baker, James R., Schotsaert, Michael, Wong, Pamela T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882683/ https://www.ncbi.nlm.nih.gov/pubmed/36711479 http://dx.doi.org/10.21203/rs.3.rs-2457013/v1 |
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