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Oxytocin receptor DNA methylation is associated with exogenous oxytocin needs during parturition and postpartum hemorrhage

BACKGROUND: The oxytocin receptor gene (OXTR) is regulated, in part, by DNA methylation. This mechanism has implications for uterine contractility during labor and for prevention or treatment of postpartum hemorrhage, an important contributor to global maternal morbidity and mortality. METHODS: We m...

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Detalles Bibliográficos
Autores principales: Erickson, Elise N., Myatt, Leslie, Danoff, Joshua S., Krol, Kathleen M., Connelly, Jessica J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882749/
https://www.ncbi.nlm.nih.gov/pubmed/36707542
http://dx.doi.org/10.1038/s43856-023-00244-6