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Force-Dependent Folding Kinetics of Single Molecules with Multiple Intermediates and Pathways

[Image: see text] Most single-molecule studies derive the kinetic rates of native, intermediate, and unfolded states from equilibrium hopping experiments. Here, we apply the Kramers kinetic diffusive model to derive the force-dependent kinetic rates of intermediate states from nonequilibrium pulling...

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Detalles Bibliográficos
Autores principales: Rico-Pasto, Marc, Alemany, Anna, Ritort, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882750/
https://www.ncbi.nlm.nih.gov/pubmed/35072478
http://dx.doi.org/10.1021/acs.jpclett.1c03521

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