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Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant

Iodine-V ((C(26)H(39)N(4)O(15))(x) * (I(2))(y)) demonstrates an in vitro virucidal activity by deactivating SARS-CoV-2 viral titers. It combines elemental iodine (I(2)) and fulvic acid (C(14)H(12)O(8)), forming a clathrate compound. The antiviral properties of Iodine-V reduce viral load in the air t...

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Detalles Bibliográficos
Autor principal: Köntös, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882904/
https://www.ncbi.nlm.nih.gov/pubmed/36706113
http://dx.doi.org/10.1371/journal.pone.0279027
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author Köntös, Zoltán
author_facet Köntös, Zoltán
author_sort Köntös, Zoltán
collection PubMed
description Iodine-V ((C(26)H(39)N(4)O(15))(x) * (I(2))(y)) demonstrates an in vitro virucidal activity by deactivating SARS-CoV-2 viral titers. It combines elemental iodine (I(2)) and fulvic acid (C(14)H(12)O(8)), forming a clathrate compound. The antiviral properties of Iodine-V reduce viral load in the air to inhibit viral transmission indoors. This antiviral property was applied to form a disinfectant solution called SAFEAIR-X Aerosol. The current study evaluates the antiviral efficacy of Iodine-V in aerosol form in a prototype called SAFEAIR-X Aerosol. The experiment measured the antiviral efficacy of SAFEAIR-X following exposure to the Vaccinia virus (VACV) samples as a confirmed surrogate for SARS-CoV-2. The SAFEAIR-X showed 96% effectiveness, with 2 seconds of spraying duration and 60 seconds of contact time releasing less than 0.0001 ppm of iodine into the air, and a log reduction value of 1.50 at 60 seconds in 2 out of 3 tests was observed. Therefore, this study demonstrates SAFEAIR-X aerosol as a potential indoor surface and air disinfectant.
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spelling pubmed-98829042023-01-28 Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant Köntös, Zoltán PLoS One Research Article Iodine-V ((C(26)H(39)N(4)O(15))(x) * (I(2))(y)) demonstrates an in vitro virucidal activity by deactivating SARS-CoV-2 viral titers. It combines elemental iodine (I(2)) and fulvic acid (C(14)H(12)O(8)), forming a clathrate compound. The antiviral properties of Iodine-V reduce viral load in the air to inhibit viral transmission indoors. This antiviral property was applied to form a disinfectant solution called SAFEAIR-X Aerosol. The current study evaluates the antiviral efficacy of Iodine-V in aerosol form in a prototype called SAFEAIR-X Aerosol. The experiment measured the antiviral efficacy of SAFEAIR-X following exposure to the Vaccinia virus (VACV) samples as a confirmed surrogate for SARS-CoV-2. The SAFEAIR-X showed 96% effectiveness, with 2 seconds of spraying duration and 60 seconds of contact time releasing less than 0.0001 ppm of iodine into the air, and a log reduction value of 1.50 at 60 seconds in 2 out of 3 tests was observed. Therefore, this study demonstrates SAFEAIR-X aerosol as a potential indoor surface and air disinfectant. Public Library of Science 2023-01-27 /pmc/articles/PMC9882904/ /pubmed/36706113 http://dx.doi.org/10.1371/journal.pone.0279027 Text en © 2023 Zoltán Köntös https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Köntös, Zoltán
Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant
title Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant
title_full Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant
title_fullStr Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant
title_full_unstemmed Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant
title_short Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant
title_sort reducing vaccinia virus transmission indoors within 60 seconds: applying safeair-x aerosol with iodine-v as a disinfectant
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882904/
https://www.ncbi.nlm.nih.gov/pubmed/36706113
http://dx.doi.org/10.1371/journal.pone.0279027
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