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Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant
Iodine-V ((C(26)H(39)N(4)O(15))(x) * (I(2))(y)) demonstrates an in vitro virucidal activity by deactivating SARS-CoV-2 viral titers. It combines elemental iodine (I(2)) and fulvic acid (C(14)H(12)O(8)), forming a clathrate compound. The antiviral properties of Iodine-V reduce viral load in the air t...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882904/ https://www.ncbi.nlm.nih.gov/pubmed/36706113 http://dx.doi.org/10.1371/journal.pone.0279027 |
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author | Köntös, Zoltán |
author_facet | Köntös, Zoltán |
author_sort | Köntös, Zoltán |
collection | PubMed |
description | Iodine-V ((C(26)H(39)N(4)O(15))(x) * (I(2))(y)) demonstrates an in vitro virucidal activity by deactivating SARS-CoV-2 viral titers. It combines elemental iodine (I(2)) and fulvic acid (C(14)H(12)O(8)), forming a clathrate compound. The antiviral properties of Iodine-V reduce viral load in the air to inhibit viral transmission indoors. This antiviral property was applied to form a disinfectant solution called SAFEAIR-X Aerosol. The current study evaluates the antiviral efficacy of Iodine-V in aerosol form in a prototype called SAFEAIR-X Aerosol. The experiment measured the antiviral efficacy of SAFEAIR-X following exposure to the Vaccinia virus (VACV) samples as a confirmed surrogate for SARS-CoV-2. The SAFEAIR-X showed 96% effectiveness, with 2 seconds of spraying duration and 60 seconds of contact time releasing less than 0.0001 ppm of iodine into the air, and a log reduction value of 1.50 at 60 seconds in 2 out of 3 tests was observed. Therefore, this study demonstrates SAFEAIR-X aerosol as a potential indoor surface and air disinfectant. |
format | Online Article Text |
id | pubmed-9882904 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-98829042023-01-28 Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant Köntös, Zoltán PLoS One Research Article Iodine-V ((C(26)H(39)N(4)O(15))(x) * (I(2))(y)) demonstrates an in vitro virucidal activity by deactivating SARS-CoV-2 viral titers. It combines elemental iodine (I(2)) and fulvic acid (C(14)H(12)O(8)), forming a clathrate compound. The antiviral properties of Iodine-V reduce viral load in the air to inhibit viral transmission indoors. This antiviral property was applied to form a disinfectant solution called SAFEAIR-X Aerosol. The current study evaluates the antiviral efficacy of Iodine-V in aerosol form in a prototype called SAFEAIR-X Aerosol. The experiment measured the antiviral efficacy of SAFEAIR-X following exposure to the Vaccinia virus (VACV) samples as a confirmed surrogate for SARS-CoV-2. The SAFEAIR-X showed 96% effectiveness, with 2 seconds of spraying duration and 60 seconds of contact time releasing less than 0.0001 ppm of iodine into the air, and a log reduction value of 1.50 at 60 seconds in 2 out of 3 tests was observed. Therefore, this study demonstrates SAFEAIR-X aerosol as a potential indoor surface and air disinfectant. Public Library of Science 2023-01-27 /pmc/articles/PMC9882904/ /pubmed/36706113 http://dx.doi.org/10.1371/journal.pone.0279027 Text en © 2023 Zoltán Köntös https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Köntös, Zoltán Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant |
title | Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant |
title_full | Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant |
title_fullStr | Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant |
title_full_unstemmed | Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant |
title_short | Reducing Vaccinia virus transmission indoors within 60 seconds: Applying SAFEAIR-X aerosol with Iodine-V as a disinfectant |
title_sort | reducing vaccinia virus transmission indoors within 60 seconds: applying safeair-x aerosol with iodine-v as a disinfectant |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882904/ https://www.ncbi.nlm.nih.gov/pubmed/36706113 http://dx.doi.org/10.1371/journal.pone.0279027 |
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