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Optineurin regulates NRF2-mediated antioxidant response in a mouse model of Paget’s disease of bone

Degenerative diseases affecting the nervous and skeletal systems affect the health of millions of elderly people. Optineurin (OPTN) has been associated with numerous neurodegenerative diseases and Paget’s disease of bone (PDB), a degenerative bone disease initiated by hyperactive osteoclastogenesis....

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Detalles Bibliográficos
Autores principales:	Hu, Xiangxiang, Wong, Sing-Wai, Liang, Kaixin, Wu, Tai-Hsien, Wang, Sheng, Wang, Lufei, Liu, Jie, Yamauchi, Mitsuo, Foster, Brian L., Ting, Jenny P.-Y., Zhao, Baohong, Tseng, Henry C., Ko, Ching-Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882986/ https://www.ncbi.nlm.nih.gov/pubmed/36706179 http://dx.doi.org/10.1126/sciadv.ade6998

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