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Optineurin regulates NRF2-mediated antioxidant response in a mouse model of Paget’s disease of bone
Degenerative diseases affecting the nervous and skeletal systems affect the health of millions of elderly people. Optineurin (OPTN) has been associated with numerous neurodegenerative diseases and Paget’s disease of bone (PDB), a degenerative bone disease initiated by hyperactive osteoclastogenesis....
Autores principales: | Hu, Xiangxiang, Wong, Sing-Wai, Liang, Kaixin, Wu, Tai-Hsien, Wang, Sheng, Wang, Lufei, Liu, Jie, Yamauchi, Mitsuo, Foster, Brian L., Ting, Jenny P.-Y., Zhao, Baohong, Tseng, Henry C., Ko, Ching-Chang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9882986/ https://www.ncbi.nlm.nih.gov/pubmed/36706179 http://dx.doi.org/10.1126/sciadv.ade6998 |
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