An Unusual Presentation of a Patient With Low-Dose Methotrexate Causing Colitis and Pancytopenia

This paper summarizes the case of a patient admitted to the hospital due to methotrexate-induced colitis in the setting of pancytopenia. Although methotrexate is commonly used for a variety of diseases, this medication can precipitate side effects in a subset of patients. This is an atypical case of...

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Autores principales: R, Ramya, Malic, Nikola, Menon, Trishala, Marks, Edward, Machani, Sathyanarayana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Medical Education
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883061/
https://www.ncbi.nlm.nih.gov/pubmed/36721611
http://dx.doi.org/10.7759/cureus.33062
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author R, Ramya
Malic, Nikola
Menon, Trishala
Marks, Edward
Machani, Sathyanarayana
author_facet R, Ramya
Malic, Nikola
Menon, Trishala
Marks, Edward
Machani, Sathyanarayana
author_sort R, Ramya
collection PubMed
description This paper summarizes the case of a patient admitted to the hospital due to methotrexate-induced colitis in the setting of pancytopenia. Although methotrexate is commonly used for a variety of diseases, this medication can precipitate side effects in a subset of patients. This is an atypical case of chronic low-dose methotrexate use leading to colitis and pancytopenia. It is of utmost significance to monitor patients on methotrexate through routine laboratory checks such as complete blood counts and liver function tests to ensure safety and reduce mortality.
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spelling pubmed-98830612023-01-30 An Unusual Presentation of a Patient With Low-Dose Methotrexate Causing Colitis and Pancytopenia R, Ramya Malic, Nikola Menon, Trishala Marks, Edward Machani, Sathyanarayana Cureus Medical Education This paper summarizes the case of a patient admitted to the hospital due to methotrexate-induced colitis in the setting of pancytopenia. Although methotrexate is commonly used for a variety of diseases, this medication can precipitate side effects in a subset of patients. This is an atypical case of chronic low-dose methotrexate use leading to colitis and pancytopenia. It is of utmost significance to monitor patients on methotrexate through routine laboratory checks such as complete blood counts and liver function tests to ensure safety and reduce mortality. Cureus 2022-12-28 /pmc/articles/PMC9883061/ /pubmed/36721611 http://dx.doi.org/10.7759/cureus.33062 Text en Copyright © 2022, R et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Medical Education
R, Ramya
Malic, Nikola
Menon, Trishala
Marks, Edward
Machani, Sathyanarayana
An Unusual Presentation of a Patient With Low-Dose Methotrexate Causing Colitis and Pancytopenia
title An Unusual Presentation of a Patient With Low-Dose Methotrexate Causing Colitis and Pancytopenia
title_full An Unusual Presentation of a Patient With Low-Dose Methotrexate Causing Colitis and Pancytopenia
title_fullStr An Unusual Presentation of a Patient With Low-Dose Methotrexate Causing Colitis and Pancytopenia
title_full_unstemmed An Unusual Presentation of a Patient With Low-Dose Methotrexate Causing Colitis and Pancytopenia
title_short An Unusual Presentation of a Patient With Low-Dose Methotrexate Causing Colitis and Pancytopenia
title_sort unusual presentation of a patient with low-dose methotrexate causing colitis and pancytopenia
topic Medical Education
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883061/
https://www.ncbi.nlm.nih.gov/pubmed/36721611
http://dx.doi.org/10.7759/cureus.33062
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