Alterations in platelet proteome signature and impaired platelet integrin α(IIb)β(3) activation in patients with COVID-19

BACKGROUND: Patients with COVID-19 are at increased risk of thrombosis, which is associated with altered platelet function and coagulopathy, contributing to excess mortality. OBJECTIVES: To characterize the mechanism of altered platelet function in COVID-19 patients. METHODS: The platelet proteome,...

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Detalles Bibliográficos
Autores principales: Goudswaard, Lucy J., Williams, Christopher M., Khalil, Jawad, Burley, Kate L., Hamilton, Fergus, Arnold, David, Milne, Alice, Lewis, Phil A., Heesom, Kate J., Mundell, Stuart J., Davidson, Andrew D., Poole, Alastair W., Hers, Ingeborg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. on behalf of International Society on Thrombosis and Haemostasis. 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883069/
https://www.ncbi.nlm.nih.gov/pubmed/36716966
http://dx.doi.org/10.1016/j.jtha.2023.01.018

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