Cargando…

The Role of Purine Metabolism-Related Genes PPAT and IMPDH1 in the Carcinogenesis of Intrahepatic Cholangiocarcinoma Based on Metabonomic and Bioinformatic Analyses

In this study, we investigated the role of tumor microenvironment and serum differential metabolites in intrahepatic cholangiocarcinoma (ICC) carcinogenesis, providing new evidence for ICC treatment. Serum samples from healthy individuals and ICC patients were collected for metabolomic analysis. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Chang-Jun, Ma, Zhong-Zhi, Gong, Wei-Zhi, Mao, Xian-Hai, Wen, Hao-Quan, Wang, Xiao-Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883099/ https://www.ncbi.nlm.nih.gov/pubmed/36711025 http://dx.doi.org/10.1155/2023/5141836

Ejemplares similares

Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer
por: Goswami, Moloy T., et al.
Publicado: (2015)

Posters (PDD, PMS, PNM, PPAT, POT)
Publicado: (2010)

Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation
por: O’Neill, Audrey G., et al.
Publicado: (2023)

MYBL2 regulates de novo purine synthesis by transcriptionally activating IMPDH1 in hepatocellular carcinoma cells
por: Zhao, Jun-Zhang, et al.
Publicado: (2022)

Molecular carcinogenesis of hepatocellular carcinoma and intrahepatic cholangiocarcinoma: one step closer to personalized medicine?
por: Kumar, Mia, et al.
Publicado: (2011)

Development and validation of a Prototype Prakriti Analysis Tool (PPAT): Inferences from a pilot study
por: Rastogi, Sanjeev
Publicado: (2012)

Intrahepatic Sarcomatoid Cholangiocarcinoma
por: Malhotra, Shalini, et al.
Publicado: (2010)

Asbestos and Intrahepatic Cholangiocarcinoma
por: Brandi, Giovanni, et al.
Publicado: (2020)

Management of Intrahepatic Cholangiocarcinoma
por: Kodali, Sudha, et al.
Publicado: (2021)

Translational Bioinformatics for Cholangiocarcinoma: Opportunities and Challenges
por: Qian, Fuliang, et al.
Publicado: (2018)

The diagnostic and prognostic value of UBE2T in intrahepatic cholangiocarcinoma
por: Yu, Hua, et al.
Publicado: (2020)

An Efficient Nomogram for Discriminating Intrahepatic Cholangiocarcinoma From Hepatocellular Carcinoma: A Retrospective Study
por: Si, Yuan-Quan, et al.
Publicado: (2022)

Cytoophidium assembly reflects upregulation of IMPDH activity
por: Chang, Chia-Chun, et al.
Publicado: (2015)

Interfilament interaction between IMPDH and CTPS cytoophidia
por: Chang, Chia‐Chun, et al.
Publicado: (2018)

IMPDH dysregulation in disease: a mini review
por: Burrell, Anika L., et al.
Publicado: (2022)

Downregulation of Fat Mass and Obesity Associated (FTO) Promotes the Progression of Intrahepatic Cholangiocarcinoma
por: Rong, Zhuo-Xian, et al.
Publicado: (2019)

Two Varieties of Intrahepatic Cholangiocarcinoma
por: Nagorney, David M.
Publicado: (1994)

Intrahepatic Cholangiocarcinoma with Sarcomatous Changes
por: Inoue, Yoshiyuki, et al.
Publicado: (2012)

Serum Markers of Intrahepatic Cholangiocarcinoma
por: Malaguarnera, Giulia, et al.
Publicado: (2013)

Intrahepatic cholangiocarcinoma: current perspectives
por: Buettner, Stefan, et al.
Publicado: (2017)

Intratumoral heterogeneity of intrahepatic cholangiocarcinoma
por: Walter, Dirk, et al.
Publicado: (2017)

Molecular heterogeneity in intrahepatic cholangiocarcinoma
por: Ahn, Keun Soo, et al.
Publicado: (2020)

Recurrent Intrahepatic Cholangiocarcinoma – Review
por: Bekki, Yuki, et al.
Publicado: (2021)

Stereotactic radiotherapy for intrahepatic cholangiocarcinoma
por: Borakati, Aditya, et al.
Publicado: (2022)

Surgical Aspects of Intrahepatic Cholangiocarcinoma
por: Kupietzky, Amram, et al.
Publicado: (2022)

Locoregional Therapy for Intrahepatic Cholangiocarcinoma
por: Owen, Mackenzie, et al.
Publicado: (2023)

Macroscopic types of intrahepatic cholangiocarcinoma and the eighth edition of AJCC/UICC TNM staging system
por: Meng, Ze-Wu, et al.
Publicado: (2017)

A novel murine model of combined hepatocellular carcinoma and intrahepatic cholangiocarcinoma
por: Xu, Ru-Chen, et al.
Publicado: (2022)

Impact of cirrhosis on long‐term survival outcomes of patients with intrahepatic cholangiocarcinoma
por: Wang, Jian, et al.
Publicado: (2022)

INTS8 is a therapeutic target for intrahepatic cholangiocarcinoma via the integration of bioinformatics analysis and experimental validation
por: Zhou, Qi, et al.
Publicado: (2021)

IL23R as an indicator of immune infiltration and poor prognosis in intrahepatic cholangiocarcinoma: a bioinformatics analysis
por: Zhang, Lin-Ting, et al.
Publicado: (2023)

A case of toxic epidermal necrolysis associated with lenvatinib and sintilimab therapy for intrahepatic cholangiocarcinoma
por: Gong, Yinhua, et al.
Publicado: (2023)

Tumor-associated lymphangiogenesis predicts unfavorable prognosis of intrahepatic cholangiocarcinoma
por: Sha, Meng, et al.
Publicado: (2019)

Intrahepatic cholangiocarcinoma arising in Caroli's disease
por: Jang, Min Hye, et al.
Publicado: (2014)

The role of microRNAs in intrahepatic cholangiocarcinoma
por: Li, Zheng, et al.
Publicado: (2016)

Prostatic metastasis from intrahepatic cholangiocarcinoma
por: Tosev, Georgi, et al.
Publicado: (2018)

Systemic and Adjuvant Therapies for Intrahepatic Cholangiocarcinoma
por: Chun, Yun Shin, et al.
Publicado: (2017)

Epidemiology of Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma
por: Massarweh, Nader N., et al.
Publicado: (2017)

The construction of intrahepatic cholangiocarcinoma model in zebrafish
por: Wang, Jing, et al.
Publicado: (2017)

Neoadjuvant treatment strategies for intrahepatic cholangiocarcinoma
por: Akateh, Clifford, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_84kdmk0oela9efglig5nel74m2