SMARCB1(INI-1)-Deficient Sinonasal Carcinoma: An Evolving Entity

SMARCB1(INI-1)-deficient sinonasal carcinoma is a rare, poorly differentiated neoplasm with a poor prognosis. Though historically most were identified as sinonasal undifferentiated carcinoma, we now understand it to be a distinct entity. There is currently a general consensus supporting multimodal t...

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Autores principales: Chung, Sei Y., Kenee, Parker, Mitton, Tanner, Halderman, Ashleigh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883109/
https://www.ncbi.nlm.nih.gov/pubmed/36712411
http://dx.doi.org/10.1055/a-1996-1283
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author Chung, Sei Y.
Kenee, Parker
Mitton, Tanner
Halderman, Ashleigh
author_facet Chung, Sei Y.
Kenee, Parker
Mitton, Tanner
Halderman, Ashleigh
author_sort Chung, Sei Y.
collection PubMed
description SMARCB1(INI-1)-deficient sinonasal carcinoma is a rare, poorly differentiated neoplasm with a poor prognosis. Though historically most were identified as sinonasal undifferentiated carcinoma, we now understand it to be a distinct entity. There is currently a general consensus supporting multimodal therapy, though the optimal sequence of surgery, chemotherapy, and radiation has yet to be defined.
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spelling pubmed-98831092023-01-28 SMARCB1(INI-1)-Deficient Sinonasal Carcinoma: An Evolving Entity Chung, Sei Y. Kenee, Parker Mitton, Tanner Halderman, Ashleigh J Neurol Surg Rep SMARCB1(INI-1)-deficient sinonasal carcinoma is a rare, poorly differentiated neoplasm with a poor prognosis. Though historically most were identified as sinonasal undifferentiated carcinoma, we now understand it to be a distinct entity. There is currently a general consensus supporting multimodal therapy, though the optimal sequence of surgery, chemotherapy, and radiation has yet to be defined. Georg Thieme Verlag KG 2023-01-16 /pmc/articles/PMC9883109/ /pubmed/36712411 http://dx.doi.org/10.1055/a-1996-1283 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Chung, Sei Y.
Kenee, Parker
Mitton, Tanner
Halderman, Ashleigh
SMARCB1(INI-1)-Deficient Sinonasal Carcinoma: An Evolving Entity
title SMARCB1(INI-1)-Deficient Sinonasal Carcinoma: An Evolving Entity
title_full SMARCB1(INI-1)-Deficient Sinonasal Carcinoma: An Evolving Entity
title_fullStr SMARCB1(INI-1)-Deficient Sinonasal Carcinoma: An Evolving Entity
title_full_unstemmed SMARCB1(INI-1)-Deficient Sinonasal Carcinoma: An Evolving Entity
title_short SMARCB1(INI-1)-Deficient Sinonasal Carcinoma: An Evolving Entity
title_sort smarcb1(ini-1)-deficient sinonasal carcinoma: an evolving entity
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883109/
https://www.ncbi.nlm.nih.gov/pubmed/36712411
http://dx.doi.org/10.1055/a-1996-1283
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