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Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity
Dynamic changes in cell properties lead to intratumor heterogeneity; however, the mechanisms of nongenetic cellular plasticity remain elusive. When the fate of each cell from colorectal cancer organoids was tracked through a clonogenic growth assay, the cells showed a wide range of growth ability ev...
Autores principales: | Coppo, Roberto, Kondo, Jumpei, Iida, Keita, Okada, Mariko, Onuma, Kunishige, Tanaka, Yoshihisa, Kamada, Mayumi, Ohue, Masayuki, Kawada, Kenji, Obama, Kazutaka, Inoue, Masahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883198/ https://www.ncbi.nlm.nih.gov/pubmed/36718360 http://dx.doi.org/10.1016/j.isci.2023.105962 |
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