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Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity

Dynamic changes in cell properties lead to intratumor heterogeneity; however, the mechanisms of nongenetic cellular plasticity remain elusive. When the fate of each cell from colorectal cancer organoids was tracked through a clonogenic growth assay, the cells showed a wide range of growth ability ev...

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Detalles Bibliográficos
Autores principales: Coppo, Roberto, Kondo, Jumpei, Iida, Keita, Okada, Mariko, Onuma, Kunishige, Tanaka, Yoshihisa, Kamada, Mayumi, Ohue, Masayuki, Kawada, Kenji, Obama, Kazutaka, Inoue, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883198/
https://www.ncbi.nlm.nih.gov/pubmed/36718360
http://dx.doi.org/10.1016/j.isci.2023.105962

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