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Stromal peeling for deep anterior lamellar keratoplasty in a post-penetrating keratoplasty eye with hematocornea

PURPOSE: To present a case of hematocornea occurring in a post-penetrating keratoplasty (PK) eye and to report the outcomes of deep anterior lamellar keratoplasty (DALK) performed by simple stromal peeling. OBSERVATIONS: A 45-year-old female presented with hematocornea in the left eye that previousl...

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Autores principales: Scorcia, Vincenzo, Giannaccare, Giuseppe, Pellegrini, Marco, Camposampiero, Davide, Ponzin, Diego, Yu, Angeli Christy, Busin, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883201/
https://www.ncbi.nlm.nih.gov/pubmed/36718436
http://dx.doi.org/10.1016/j.ajoc.2023.101808
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author Scorcia, Vincenzo
Giannaccare, Giuseppe
Pellegrini, Marco
Camposampiero, Davide
Ponzin, Diego
Yu, Angeli Christy
Busin, Massimo
author_facet Scorcia, Vincenzo
Giannaccare, Giuseppe
Pellegrini, Marco
Camposampiero, Davide
Ponzin, Diego
Yu, Angeli Christy
Busin, Massimo
author_sort Scorcia, Vincenzo
collection PubMed
description PURPOSE: To present a case of hematocornea occurring in a post-penetrating keratoplasty (PK) eye and to report the outcomes of deep anterior lamellar keratoplasty (DALK) performed by simple stromal peeling. OBSERVATIONS: A 45-year-old female presented with hematocornea in the left eye that previously underwent PK 26 months prior for keratoconus. Clinical examination revealed a dense reddish-brown opacity within the PK graft which was associated with deep corneal neovascularization. Over 6 months, intracorneal hemorrhage developed a rust-colored appearance with minimal clearing. DALK was performed using the stromal peeling technique for post-PK eyes. Briefly, a dense partially organized hemorrhage was identified at the natural plane of separation, as confirmed by ex vivo histologic examination; after peeling of the deep corneal stroma and evacuation of the intracorneal hemorrhage, the residual bed appeared akin to pre-Descemet's layer–Descemet membrane–endothelium complex. One year after DALK, the graft remained clear with ECD of 1034 cells/mm(2). CONCLUSIONS AND IMPORTANCE: Intracorneal hemorrhage is a rare but potentially sight-threatening complication following PK. Using the stromal peeling technique, DALK can be attempted to preserve functional endothelium in post-PK eyes. In the presence of a dense intracorneal hemorrhage, the spread of erythrocytic debris within the stroma can guide deep lamellar cleavage.
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spelling pubmed-98832012023-01-29 Stromal peeling for deep anterior lamellar keratoplasty in a post-penetrating keratoplasty eye with hematocornea Scorcia, Vincenzo Giannaccare, Giuseppe Pellegrini, Marco Camposampiero, Davide Ponzin, Diego Yu, Angeli Christy Busin, Massimo Am J Ophthalmol Case Rep Case Report PURPOSE: To present a case of hematocornea occurring in a post-penetrating keratoplasty (PK) eye and to report the outcomes of deep anterior lamellar keratoplasty (DALK) performed by simple stromal peeling. OBSERVATIONS: A 45-year-old female presented with hematocornea in the left eye that previously underwent PK 26 months prior for keratoconus. Clinical examination revealed a dense reddish-brown opacity within the PK graft which was associated with deep corneal neovascularization. Over 6 months, intracorneal hemorrhage developed a rust-colored appearance with minimal clearing. DALK was performed using the stromal peeling technique for post-PK eyes. Briefly, a dense partially organized hemorrhage was identified at the natural plane of separation, as confirmed by ex vivo histologic examination; after peeling of the deep corneal stroma and evacuation of the intracorneal hemorrhage, the residual bed appeared akin to pre-Descemet's layer–Descemet membrane–endothelium complex. One year after DALK, the graft remained clear with ECD of 1034 cells/mm(2). CONCLUSIONS AND IMPORTANCE: Intracorneal hemorrhage is a rare but potentially sight-threatening complication following PK. Using the stromal peeling technique, DALK can be attempted to preserve functional endothelium in post-PK eyes. In the presence of a dense intracorneal hemorrhage, the spread of erythrocytic debris within the stroma can guide deep lamellar cleavage. Elsevier 2023-01-22 /pmc/articles/PMC9883201/ /pubmed/36718436 http://dx.doi.org/10.1016/j.ajoc.2023.101808 Text en © 2023 The Authors. Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Scorcia, Vincenzo
Giannaccare, Giuseppe
Pellegrini, Marco
Camposampiero, Davide
Ponzin, Diego
Yu, Angeli Christy
Busin, Massimo
Stromal peeling for deep anterior lamellar keratoplasty in a post-penetrating keratoplasty eye with hematocornea
title Stromal peeling for deep anterior lamellar keratoplasty in a post-penetrating keratoplasty eye with hematocornea
title_full Stromal peeling for deep anterior lamellar keratoplasty in a post-penetrating keratoplasty eye with hematocornea
title_fullStr Stromal peeling for deep anterior lamellar keratoplasty in a post-penetrating keratoplasty eye with hematocornea
title_full_unstemmed Stromal peeling for deep anterior lamellar keratoplasty in a post-penetrating keratoplasty eye with hematocornea
title_short Stromal peeling for deep anterior lamellar keratoplasty in a post-penetrating keratoplasty eye with hematocornea
title_sort stromal peeling for deep anterior lamellar keratoplasty in a post-penetrating keratoplasty eye with hematocornea
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883201/
https://www.ncbi.nlm.nih.gov/pubmed/36718436
http://dx.doi.org/10.1016/j.ajoc.2023.101808
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