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A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis

A compartmental mathematical model of spreading COVID-19 disease in Wuhan, China is applied to investigate the pandemic behaviour in Iran. This model is a system of seven ordinary differential equations including individual behavioural reactions, governmental actions, holiday extensions, travel rest...

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Detalles Bibliográficos
Autores principales: Sadri, Khadijeh, Aminikhah, Hossein, Aminikhah, Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883209/
https://www.ncbi.nlm.nih.gov/pubmed/36742367
http://dx.doi.org/10.1016/j.mex.2023.102045
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author Sadri, Khadijeh
Aminikhah, Hossein
Aminikhah, Mahdi
author_facet Sadri, Khadijeh
Aminikhah, Hossein
Aminikhah, Mahdi
author_sort Sadri, Khadijeh
collection PubMed
description A compartmental mathematical model of spreading COVID-19 disease in Wuhan, China is applied to investigate the pandemic behaviour in Iran. This model is a system of seven ordinary differential equations including individual behavioural reactions, governmental actions, holiday extensions, travel restrictions, hospitalizations, and quarantine. We fit the Chinese model to the Covid-19 outbreak in Iran and estimate the values of parameters by trial-error approach. We use the Adams-Bashforth predictor-corrector method based on Lagrange polynomials to solve the system of ordinary differential equations. To prove the existence and uniqueness of solutions of the model we use Banach fixed point theorem and Picard iterative method. Also, we evaluate the equilibrium points and the stability of the system. With estimating the basic reproduction number [Formula: see text] , we assess the trend of new infected cases in Iran. In addition, the sensitivity analysis of the model is assessed by allocating different parameters to the system. Numerical simulations are depicted by adopting initial conditions and various values of some parameters of the system.
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spelling pubmed-98832092023-01-30 A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis Sadri, Khadijeh Aminikhah, Hossein Aminikhah, Mahdi MethodsX Review Article A compartmental mathematical model of spreading COVID-19 disease in Wuhan, China is applied to investigate the pandemic behaviour in Iran. This model is a system of seven ordinary differential equations including individual behavioural reactions, governmental actions, holiday extensions, travel restrictions, hospitalizations, and quarantine. We fit the Chinese model to the Covid-19 outbreak in Iran and estimate the values of parameters by trial-error approach. We use the Adams-Bashforth predictor-corrector method based on Lagrange polynomials to solve the system of ordinary differential equations. To prove the existence and uniqueness of solutions of the model we use Banach fixed point theorem and Picard iterative method. Also, we evaluate the equilibrium points and the stability of the system. With estimating the basic reproduction number [Formula: see text] , we assess the trend of new infected cases in Iran. In addition, the sensitivity analysis of the model is assessed by allocating different parameters to the system. Numerical simulations are depicted by adopting initial conditions and various values of some parameters of the system. Elsevier 2023-01-28 /pmc/articles/PMC9883209/ /pubmed/36742367 http://dx.doi.org/10.1016/j.mex.2023.102045 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Sadri, Khadijeh
Aminikhah, Hossein
Aminikhah, Mahdi
A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis
title A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis
title_full A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis
title_fullStr A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis
title_full_unstemmed A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis
title_short A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis
title_sort mathematical system of covid-19 disease model: existence, uniqueness, numerical and sensitivity analysis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883209/
https://www.ncbi.nlm.nih.gov/pubmed/36742367
http://dx.doi.org/10.1016/j.mex.2023.102045
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