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A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis
A compartmental mathematical model of spreading COVID-19 disease in Wuhan, China is applied to investigate the pandemic behaviour in Iran. This model is a system of seven ordinary differential equations including individual behavioural reactions, governmental actions, holiday extensions, travel rest...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883209/ https://www.ncbi.nlm.nih.gov/pubmed/36742367 http://dx.doi.org/10.1016/j.mex.2023.102045 |
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author | Sadri, Khadijeh Aminikhah, Hossein Aminikhah, Mahdi |
author_facet | Sadri, Khadijeh Aminikhah, Hossein Aminikhah, Mahdi |
author_sort | Sadri, Khadijeh |
collection | PubMed |
description | A compartmental mathematical model of spreading COVID-19 disease in Wuhan, China is applied to investigate the pandemic behaviour in Iran. This model is a system of seven ordinary differential equations including individual behavioural reactions, governmental actions, holiday extensions, travel restrictions, hospitalizations, and quarantine. We fit the Chinese model to the Covid-19 outbreak in Iran and estimate the values of parameters by trial-error approach. We use the Adams-Bashforth predictor-corrector method based on Lagrange polynomials to solve the system of ordinary differential equations. To prove the existence and uniqueness of solutions of the model we use Banach fixed point theorem and Picard iterative method. Also, we evaluate the equilibrium points and the stability of the system. With estimating the basic reproduction number [Formula: see text] , we assess the trend of new infected cases in Iran. In addition, the sensitivity analysis of the model is assessed by allocating different parameters to the system. Numerical simulations are depicted by adopting initial conditions and various values of some parameters of the system. |
format | Online Article Text |
id | pubmed-9883209 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-98832092023-01-30 A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis Sadri, Khadijeh Aminikhah, Hossein Aminikhah, Mahdi MethodsX Review Article A compartmental mathematical model of spreading COVID-19 disease in Wuhan, China is applied to investigate the pandemic behaviour in Iran. This model is a system of seven ordinary differential equations including individual behavioural reactions, governmental actions, holiday extensions, travel restrictions, hospitalizations, and quarantine. We fit the Chinese model to the Covid-19 outbreak in Iran and estimate the values of parameters by trial-error approach. We use the Adams-Bashforth predictor-corrector method based on Lagrange polynomials to solve the system of ordinary differential equations. To prove the existence and uniqueness of solutions of the model we use Banach fixed point theorem and Picard iterative method. Also, we evaluate the equilibrium points and the stability of the system. With estimating the basic reproduction number [Formula: see text] , we assess the trend of new infected cases in Iran. In addition, the sensitivity analysis of the model is assessed by allocating different parameters to the system. Numerical simulations are depicted by adopting initial conditions and various values of some parameters of the system. Elsevier 2023-01-28 /pmc/articles/PMC9883209/ /pubmed/36742367 http://dx.doi.org/10.1016/j.mex.2023.102045 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Sadri, Khadijeh Aminikhah, Hossein Aminikhah, Mahdi A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis |
title | A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis |
title_full | A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis |
title_fullStr | A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis |
title_full_unstemmed | A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis |
title_short | A mathematical system of COVID-19 disease model: Existence, uniqueness, numerical and sensitivity analysis |
title_sort | mathematical system of covid-19 disease model: existence, uniqueness, numerical and sensitivity analysis |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883209/ https://www.ncbi.nlm.nih.gov/pubmed/36742367 http://dx.doi.org/10.1016/j.mex.2023.102045 |
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