Cargando…
Thioalbamide inhibits F(o)F(1)-ATPase in breast cancer cells and reduces tumor proliferation and invasiveness in breast cancer in vivo models
OBJECTIVE: Thioalbamide is a ribosomally synthesized and post-translationally modified peptide (RiPP) belonging to the family of thioamitides, a rare class of microbial specialized metabolites with unusual post-translational modifications and promising biological activities. Recent studies have demo...
Autores principales: | Frattaruolo, L., Malivindi, R., Brindisi, M., Rago, V., Curcio, R., Lauria, G., Fiorillo, M., Dolce, V., Truman, A.W., Cappello, A.R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883262/ https://www.ncbi.nlm.nih.gov/pubmed/36657563 http://dx.doi.org/10.1016/j.molmet.2023.101674 |
Ejemplares similares
-
Thioalbamide, A Thioamidated Peptide from Amycolatopsis alba, Affects Tumor Growth and Stemness by Inducing Metabolic Dysfunction and Oxidative Stress
por: Frattaruolo, Luca, et al.
Publicado: (2019) -
5-(Carbamoylmethylene)-oxazolidin-2-ones as a Promising Class of Heterocycles Inducing Apoptosis Triggered by Increased ROS Levels and Mitochondrial Dysfunction in Breast and Cervical Cancer
por: Armentano, Biagio, et al.
Publicado: (2020) -
Targeting the Mitochondrial Metabolic Network: A Promising Strategy in Cancer Treatment
por: Frattaruolo, Luca, et al.
Publicado: (2020) -
Smart Lipid–Polysaccharide Nanoparticles for Targeted Delivery of Doxorubicin to Breast Cancer Cells
por: Curcio, Manuela, et al.
Publicado: (2022) -
Cholesterol and Mevalonate: Two Metabolites Involved in Breast Cancer Progression and Drug Resistance through the ERRα Pathway
por: Brindisi, Matteo, et al.
Publicado: (2020)