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Hepatitis C virus replication requires integrity of mitochondria-associated ER membranes

BACKGROUND & AIMS: Chronic HCV infection causes cellular stress, fibrosis and predisposes to hepatocarcinogenesis. Mitochondria play key roles in orchestrating stress responses by regulating bioenergetics, inflammation and apoptosis. To better understand the role of mitochondria in the viral lif...

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Detalles Bibliográficos
Autores principales: Duponchel, Sarah, Monnier, Lea, Molle, Jennifer, Bendridi, Nadia, Alam, Muhammad Rizwan, Gaballah, Ahmed, Grigorov, Boyan, Ivanov, Alexander, Schmiel, Marcel, Odenthal, Margarete, Ovize, Michel, Rieusset, Jennifer, Zoulim, Fabien, Bartosch, Birke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883273/
https://www.ncbi.nlm.nih.gov/pubmed/36718430
http://dx.doi.org/10.1016/j.jhepr.2022.100647